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mrsa 12673  (ATCC)


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    Structured Review

    ATCC mrsa 12673
    Mrsa 12673, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mrsa+12673/Nocardioides+nitrophenolicus+Yoon+et+al/pmc12562379-140-34-31
    Average 90 stars, based on 18 article reviews
    mrsa 12673 - by Bioz Stars, 2026-11
    90/100 stars

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    Activity Assay:

    Article Title: Facile Synthesis of N -vinylindoles via Knoevenagel Condensation: Molecular Features and Biological Activities
    Article Snippet: In turn, analogs 2b and 2g bearing p -tolyl and 4-nitrophenyl groups as the R substituents, respectively, showed moderate activity against S. aureus ATCC 6535 (MIC = 55 μg/mL, MBC = 110 μg/mL), whereas the activity of N -vinylindole derivatives with phenyl (compound 2a , R = C 6 H 5 ), 4-methoxyphenyl (compound 2c , R = 4-CH 3 O-C 6 H 4 ) or 4-fluorophenyl (compound 2d , R = 4-F-C 6 H 4 ) substituents R toward the two strains of S. aureus was low (MIC = 110–220 μg/mL, MBC = 220–240 μg/mL). .. Among all the compounds evaluated, the highest antibacterial activity was observed for compound 2i , which features a 2-naphthyl substituent R. This derivative demonstrated pronounced potential against both S. aureus strains, ATCC 6535 and MRSA 12673, with MIC values of 15 μg/mL and 30 μg/mL, respectively, and MBC values of 30 μg/mL. .. In addition, N -vinylindole 2i was characterized by relatively good antifungal activity against C. glabrata ATCC 2001, with MIC and MFC values of 60 μg/mL.



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